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Cedars-Sinai Postdoctoral Scientist - Arditi Lab in Los Angeles, California

The Cedars-Sinai Infectious and Immunological Diseases Research Center (IIDRC) Department of Biomedical Sciences and the Pediatrics Department (Arditi Lab) are seeking a highly motivated Postdoctoral Research Scientist, for NIH-funded cardiovascular immunobiology and mitochondrial biology research.

The Arditi Laboratory, led by Moshe Arditi, MD, director of the Infectious and Immunological Diseases Research Center (IIDRC), investigates innate and adaptive immunity in cardiovascular inflammation and mitochondrial biology and gender differences. The Arditi Laboratory particularly investigates the immunobiology of the cardiovascular lesions in the Kawasaki Disease vasculitis mouse model as well as abdominal aorta aneurysm and atherosclerosis mouse models, focusing in mitochondrial biology, metabolism, NLRP3 inflammasome activation and IL-1beta production.

To learn more, please visit: https://www.cedars-sinai.edu/research/labs/arditi.html

Are you looking to contribute to groundbreaking research? We look forward to having you join our team!

Working independently but in close cooperation and consultation with the Principal Investigator(s) and other Research Scientists, the Research Fellow will perform routine and complex cellular, molecular biology experiments, as well as to conduct and learn procedures for experimental murine models of cardiovascular immunobiology throughout the training period. Will develop, adapt, implement and learn new research techniques and protocols. Will analyze, interpret and present research data. Will assist in the preparation of grant proposals. Will participate in manuscript preparation and publications and abstract presentations as author or co-author.

PRIMARY JOB DUTIES and responsibilities:

  • Will assist in preparation of grant proposals and will be encouraged to apply for AHA fellowship grants.

  • Will participate in publications and presentations as author or co-author ad abstract preparations.

  • Designs and performs experiments. Will keep appropriate experimental records and documentation and analyze the results with the Principal Investigator.

  • May develop, adapt, and implement new research techniques and protocols.

  • Will analyzes, interprets, summarizes, and compiles data.

  • Will performs routine and complex laboratory procedures for experimental murine models of cardiovascular immunobiology projects throughout training period.

  • Will operates and maintains equipment and instruments. Experience in mitochondrial function and biology, in microscopic imaging and mouse dissection and experience in handling mice, including genotyping and breeding are strongly preferred.

DEPARTMENT AND/OR UNIT SPECIFIC – ESSENTIAL JOB RESPONSIBILITIES:

This is an NIH funded postdoctoral position to investigate the immunobiology of cardiovascular inflammation, including the two experimental murine models of inflammation, Kawasaki Disease vasculitis and myocarditis mouse model, and murine models of atherosclerosis. Role of innate and adaptive immunity, discovery of novel therapeutics, role of mitochondrial function and metabolism, and sex differences in these experimental models are the focus of the laboratory.

Education requirements:

  • Doctorate (PhD,) in Immunology, Immunobiology, molecular biology or areas directly related to field of research specialization.

ExperIEnce requirements:

  • Independently works on research projects designed by a mentor (typically the PI) within an area of specialization.

  • Strong background and experience in mitochondrial biology, metabolism, cellular and molecular Biology and or Immunology, as well as experience with experimental murine models of cardiovascular diseases is preferred.

  • Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection, and analysis and operation and maintenance of specialized equipment.

Cedars-Sinai is an EEO employer. Cedars-Sinai does not unlawfully discriminate on the basis of the race, religion, color, national origin, citizenship, ancestry, physical or mental disability, legally protected medical condition (cancer-related or genetic characteristics or any genetic information), marital status, sex, gender, sexual orientation, gender identity, gender expression, pregnancy, age (40 or older), military and/or veteran status or any other basis protected by federal or state law.

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