Cedars-Sinai Postdoctoral Scientist - Barrett Lab - Regenerative Medicine Institute in Los Angeles, California
An outstanding Postdoctoral Research Scientist position is available in the Barrett Laboratory at Cedars-Sinai Medical Center in Los Angeles to study mechanisms of intestinal fibrosis using an array of innovative technologies including iPSC-derived human intestinal organoids and small microengineered Chips.
The successful candidate may study cell-cell interactions and epithelial/mesenchymal cell responses to microbes and cytokines associated with fibrosis. For more information, contact Robert.Barrett@cshs.org or please see https://www.cedars-sinai.org/research/labs/barrett.html.
Working independently but in close consultation with the Principal Investigator and other Research Scientists, you will perform routine and complex laboratory procedures throughout the training period, and may develop, adapt, and implement new research techniques and protocols while analyzing and interpreting data. You will participate in publications and presentations as author or co-author and may assist in the preparation of grant proposals, but are not responsible for generating grant funds.
Job Duties and Responsibilities:
Design and perform experiments on intestinal epithelial cells derived from induced pluripotent stem cells
Generation and maintenance of induced pluripotent stem cells and intestinal organoids
Functional analysis of these intestinal organoids by ICC, qPCR, flow cytometry and western blot
Previous experience in microarray and RNAseq analysis is highly desired
Participation in laboratory meetings, keeping a lab notebook, performing calculations, tabulating data, summarizing methods and results of related experiments and general lab maintenance
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- Doctorate (MD, PhD, VMD, or DDS) in area directly related to field of research specialization
Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection, and analysis and operation and maintenance of specialized equipment.
Knowledge of safety standards and maintenance of specialized equipment.
Schedule flexibility to include evening, weekend and holiday rotation commitment required
Excellent written and oral communication skills
May require travel
Cedars-Sinai is an EEO employer. Cedars-Sinai does not unlawfully discriminate on the basis of the race, religion, color, national origin, citizenship, ancestry, physical or mental disability, legally protected medical condition (cancer-related or genetic characteristics or any genetic information), marital status, sex, gender, sexual orientation, gender identity, gender expression, pregnancy, age (40 or older), military and/or veteran status or any other basis protected by federal or state law.