Cedars-Sinai Postdoctoral Scientist - Smidt Heart Institute - Department of Cardiology - Fert-Bober Lab in Los Angeles, California
position is available at the Fert-Bober’s lab, Cedars Sinai, Smidt Heart
Institute. Our successful candidate will investigate molecular mechanisms of
cardiovascular development, regeneration and cardiac fibrosis using mass
spectrometric-based proteomics methods for the study of proteins and their
roles in cellular signaling events. We also develop
and apply the technology to the search for post-translational modified proteins,
including citrullination. Dysregulated citrullination is a key element that
drives the production and maintenance of antibodies to citrullinated proteins,
a hallmark in rheumatoid arthritis. The long-term
goal is to determine whether citrullinated proteins or antibody to
citrullinated proteins can be use as biomarkers for the early detection of many
disease, including rheumatoid arthritis, cancer and Alzheimer disease.
independently but in close consultation with the Principal Investigator and
other Research Scientists, you will perform routine and complex laboratory
procedures throughout the training period, and may develop, adapt, and
implement new research techniques and protocols while analyzing and
interpreting data. You will participate in publications and presentations as
author or co-author and may assist in the preparation of grant proposals but
are not responsible for generating grant funds.
Ph.D. and/or M.D. required
Less than 2 years of postdoctoralexperience is strongly preferred
A basicunderstanding of cardiovascular development, regeneration and cardiac fibrosisis required.
Skills inisolation and characterization of different cardiac cell types from mousehearts.
Skills in culture and maintenance of mammalian cell lines.
Skills incardiac tissue histology and proficiency in microscopy.
Experience incell manipulation, flow cytometry and cell sorting, cell tracking, and advancedcell imaging tools.
Experience instandard molecular biology techniques (eg. Cloning, qRT-PCR).
Computationalprocessing and analysis of genome scale data including RNA-seq, or proteomicsis highly desired.
Ability tomultitask and complete work on time. Ability to contribute and work in across-functional, multi-disciplinary team environment.
Good verbal andwritten communication skills in English.
Well organized,able to plan work appropriately.
Strong attention to detail.
Cedars-Sinai is an EEO employer. Cedars-Sinai does not unlawfully discriminate on the basis of the race, religion, color, national origin, citizenship, ancestry, physical or mental disability, legally protected medical condition (cancer-related or genetic characteristics or any genetic information), marital status, sex, gender, sexual orientation, gender identity, gender expression, pregnancy, age (40 or older), military and/or veteran status or any other basis protected by federal or state law.