Cedars-Sinai Project Scientist (Alzheimer's Disease) - Pathology Group Operations - Tourtellotte Lab in Los Angeles, California
The Project Scientist in the role will focus on
studying the role of microglia in Alzheimer’s Disease pathogenesis and evaluating
molecules that can augment microglial function and neurotoxic Amyloid-beta (Ab) processing and homeostasis in the brain. You must hold a doctoral degree (preferably with expertise in microglia biology and
Alzheimer’s disease, but at a minimum with neuroscience, neurobiology,
molecular biology or a closely related field).
The successful candidate should have a minimum of 3 years of experience
as a scientifically productive post-doctoral fellow and must have experience with translational
research using animal models to study mechanisms of gene function and disease
pathogenesis. Experience in molecular
biology, cell culture, immunocytochemistry, Western blotting, PCR, quantitative
real-time PCR and histology/imaging techniques including quantitative
bright-field and fluorescence microscopy and confocal microscopy is required. Experience with proteomics analysis of
isolated protein complexes will be beneficial for some of the planned protein-protein
interaction experiments. Will
be expected to independently design and conduct experiments, collect and analyze
data, troubleshoot experimental protocols, consolidate data for publication and
grant applications, present research at national and international meetings,
and prepare manuscripts for publication. Teaching and supervising other research staff, students, and residents
may be required.
You will work independently and in cooperation with the Principal Investigator to make
significant and creative contributions to the assigned research project. The research projects assigned are developed under the direction and in collaboration with the
Principal Investigator, Warren Tourtellotte, MD, PhD, Professor and Vice-Chair
of Pathology and Laboratory Medicine and Professor of Neurology, Neurosurgery
and Biomedical Sciences. You will be expected to have substantial scientific independence,
organization, creativity and motivation.
A significant track-record of scholarly productivity and strong evidence
of successful independent experimental design and execution is expected and
Summary of Essential Job
Will publishresearch as author or co-author, and present progress reports at meetings andseminars.
Analyzes, interprets,summarizes and compiles data for publication.
Maydevelop, adapt and implement new research techniques and protocols.
May assist inpreparation of grant proposals, submissions, publications and presentations,but is not responsible for generating grant funds.
May serve as PI forcertain grants as approved by Principal Investigator.
May lead or train StaffResearch Associates and Research Fellows.
Will assist inday-to-day laboratory activities.
Appointees on anacademic trajectory will be expected to commit a portion of their time todeveloping an independent range of research.
- PhD or highest degree in their field is required
Demonstrated significant, original, and creative contributions to a research or creative program or project completion of postdoctoral appointment in area of specialization, as applicable.
Completion of postdoctoral appointment in area of specialization, as applicable.Knowledge of PI’s area of research specialization.
Demonstrated technical competency in a variety of research techniques and protocols.
Cedars-Sinai is an EEO employer. Cedars-Sinai does not unlawfully discriminate on the basis of the race, religion, color, national origin, citizenship, ancestry, physical or mental disability, legally protected medical condition (cancer-related or genetic characteristics or any genetic information), marital status, sex, gender, sexual orientation, gender identity, gender expression, pregnancy, age (40 or older), military and/or veteran status or any other basis protected by federal or state law.