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Cedars-Sinai Project Scientist - Li & Han Lab - Biomedical Imaging Research Institute in Los Angeles, California

Are you ready to be a part of breakthrough research?

The Groups of Drs. Li and Han at Cedars-Sinai focuses on novel magnetic resonance hardware and methodologies for in vivo applications. To learn more, please visit: Li Research Lab | Cedars-Sinai & Han Research Lab | Cedars-Sinai .

Cedars-Sinai Medical Center, affiliated with UCLA, is a world-leading hospital and is currently ranked #7 nationally on the Best Hospitals Honor Roll. The Cedars-Sinai Biomedical Imaging Research Institute (BIRI) is one of leading MRI research groups with a central focus on developing and applying novel imaging technologies to today’s most pressing translational research and clinical questions. BIRI has been constantly growing into a team of 70 onsite personnel including research and clinician scientists, technical and support staff, postdoctoral scientists and doctoral students. BIRI has two full-time on-site MRI scientists from Siemens Healthcare.

BIRI Research Core Facility houses a state-of-the-art 3T whole-body scanner (Siemens MAGNETOM Vida), a whole-body PET/MR system (Siemens Biograph mMR) and Bruker BioSpin 9.4T small animal scanner, all dedicated to research. Other equipment includes Scanco vivaCT40 micro-CT, IVIS® Spectrum Optical Imaging System, CRi Maestro™ Fluorescence, Precision X-Ray X-RAD SmART, Notting Hill Devices Preclinical Scanner (4Dx). Our research and clinician scientists collaborate closely with physicians, especially imaging physicians, to synergistically bring together technical and clinical expertise in areas such as cardiology, neurology, and oncology imaging.

The candidate will join an interdisciplinary research group and work in an exciting, new growing field in MRI. You will focus on data acquisition and processing and publications about various imaging applications throughout the human body by leveraging our completed novel MR hardware platform that allows data acquisition in new ways previously impossible. The candidate will work closely with the MR technical team led by Dr. Debiao Li who is the founding director of BIRI. Dr. Li is a world-renowned MR physicist and is past president of the International Society for Magnetic resonance in Medicine (ISMRM). The candidate will work synergistically with the complementary MRI Hardware team led by Dr. Hui Han who is the Director of MR Engineering. He is the developer of “iPRES” MR coils for combined B0 shim and RF array, an impactful technology influencing many groups. The MRI Engineering Laboratory comprises a newly constructed lab space (2,000 sq. ft.) in the iconic Pacific Design Center in West Hollywood and a secondary lab space (150 sq. ft.) in Imaging Core Facility. Dr. Han is elected to Secretary of the Governance Committee for the ISMRM MR Engineering Study Group, who will rotate to the chair in 2023-2024 and chair the Organizing Committee for the first international ISMRM Workshop on MR Engineering to be held in LA.

The projects are funded by NIH using a collaboration effort led by Drs. Debiao Li, Hui Han, Andrew Maudsley, and Hyunsuk Shim. The desirable background and skills for the candidate may include MRI scanner experience, image acquisition and processing, MRI physics, pulse sequence development, image acquisition and processing, image reconstruction, or programming. Hands-on experience with acquisition, processing and analysis of MRI data is essential. Pulse sequence development and/or MRI reconstruction, particularly in the Siemens IDEA environment is a plus. Candidate should have a strong motivation to publish with a proven track of record. Experiences in MR hardware development are not a requirement. The candidate will benefit from a large BIRI group full of MR technical experts in pulse sequence development, image reconstruction, motion correction and artificial intelligence.

MR hardware is the basis underpinning data acquisition and image processing. Historically, MRI has been advanced by major hardware improvements such as multichannel RF detection and transmission and increased magnetic field strengths. In recent a decade, B0 shimming using localized coils becomes a rising trend in the society and combined B0 shim and RF receive arrays have drawn considerable attention. Our team has made pioneering contributions in this new field and is currently supported by multiple NIH grants. Our major effort is directed toward creating new capabilities of the existing MRI system, through developing clinically viable tools to advance the precision, fidelity, sensitivity and resolution of imaging.

The Project Scientist works independently and in cooperation with the Principal Investigators to make significant and creative contributions to a research or creative project in any academic discipline. The Project Scientist may be an ongoing member of a research team or may be employed for a limited period of time to contribute high-level skills to a specific research or creative program. Project Scientists are not required to carry out independent research or to develop an independent research reputation and do not have teaching responsibilities. Ordinarily, the Project Scientist title will carry out research or creative programs as well as administration of day-to-day lab operations with supervision by a member of the Professorial Series.

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Primary Job Duties and Responsibilities:

  • May assist in preparation of grant proposals, submissions, publications and presentations but is not responsible for generating grant funds.

  • May serve as PI for certain grants as approved by supervising member of the Professorial Series.

  • May participate in publications and presentations as author or co-author.

  • May develop, adapt and implement new research techniques and protocols.

  • Assists in lab experiments.

  • Analyzes, interprets, summarizes and compiles data.

  • May lead or train Staff Research Associates and Research Fellows. Will involve co-supervise the graduate students or research staff with less experiences.

  • Will assist in day-to-day laboratory activities.

  • Appointees on an academic trajectory will be expected to commit a portion of their time to developing an independent range of research.

Educational Requirements:

  • Doctorate degree required. Demonstrated significant, original, and creative contributions to a research or creative program or project.

Experience and Skillset:

  • Completion of postdoctoral appointment in area of specialization, as applicable

  • Knowledge of PI’s area of research specialization

  • Demonstrated technical competency in a variety of research techniques and protocols

Cedars-Sinai is an EEO employer. Cedars-Sinai does not unlawfully discriminate on the basis of the race, religion, color, national origin, citizenship, ancestry, physical or mental disability, legally protected medical condition (cancer-related or genetic characteristics or any genetic information), marital status, sex, gender, sexual orientation, gender identity, gender expression, pregnancy, age (40 or older), military and/or veteran status or any other basis protected by federal or state law.

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