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Cedars-Sinai Research Associate I in Los Angeles, California

Job Summary:

Dr. Anja Karlstaedt's laboratory is looking for a highly motivated Research Associate I interested in the

metabolic crosstalk between cardiac and cancer cells to join the Department of Cardiology within the Smidt Heart Institute at Cedars-Sinai Medical Center! Cedars-Sinai is a multidisciplinary, highly collaborative research center with an emphasis on disease and translational research.

Dr. Karlstaedt’s research focuses on the cellular mechanisms that cause heart failure in cancer patients using interdisciplinary and computational approaches. Our work has uncovered several regulatory mechanisms that explain how oncometabolic stress induces metabolic and proteomic remodeling in the heart and skeletal muscle. The challenge is now to develop strategies that target the tumor while protecting the heart.

We are looking for a highly motivated and creative scientist with a basic scientific background who is willing to learn new techniques, collaborate with postdoctoral scientists, and excited about the challenges of examining the interactions between metabolism, cancer, and immunity.

Working under direct supervision, the Research Associate I performs a variety of routine experimental protocols and procedures to support the objectives of one or more laboratory research projects in a specific area of research. Assists in general laboratory activities, including maintenance of reagents and stocking of supplies. Files and monitors documents. Keeps accurate and detailed records of experiments and results. Assists in the operation of specialized equipment and machinery. Observes safety standards and procedures. The Research Assistant I will be able to perform routine analytical, cellular, micro- and molecular biology procedures including, but not limited to mass spectrometry, ChIP-Seq, Western, Northern blot, DNA/RNA, PCR, protein extraction, cell culture, Immunohistochemistry, and staining. This position does not have supervisory responsibilities.

Primary Duties and Responsibilities:

Performs a variety of routine laboratory tasks and procedures.

Keeps accurate and detailed project records of experiments and results.

May assist with animal husbandry.

Maintains lab equipment and related records.

Transports, processes and logs samples.

Maintains computer database with relevant clinical information.

Performs lab maintenance duties, including glassware cleaning and sterilization.

Maintains stocks of general lab materials, and places orders for lab equipment and supplies.

Assists new students and fellows at the laboratory.

Independently conduct experiments planned together with the PI and post-doctoral scientist

Assists in the operation of specialized equipment and machinery.

Observes and complies with safety standards and procedures.

Maintain accurate, complete, up-to-date notes about lab work and results

Willingness to learn new techniques and an ability to follow protocol instructions

Analyze basic data sets and generate figures

Participate in regular lab meetings

Educational Requirements:

Bachelor of Science Degree in biological sciences.

Licenses:

N/A

Experience:

  • Understanding of general research objectives.

  • Some experience with some basic molecular biology techniques is an advantage (e.g., ELISA, Western Blots, protein assays, cloning, RNA and DNA isolation)

  • Prior basic experience with cell culture is desirable.

  • Coordination of tasks and activities to maximize the effectiveness of time management

  • Working knowledge of database management, personal computers, and presentation and imaging software.

  • Familiar with routine laboratory procedures and experimental protocols.

  • Must possess computer skills to include, but not limited to, Excel and Word. Additional programming experiences in R, python or perl is an advantage

Physical Demands:

  • Able to perform moderate lifting.

  • Able to sit, stand and walk for prolonged periods of time.

  • Able to read papers and online documents.

  • Able to operate standard office equipment.

  • Able to exercise physical ability and perspective acuity to satisfactorily perform essential job functions.

Working Title: Research Associate I

Department: Heart Institute Operations

Business Entity: Academic / Research

Job Category: Academic/Research

Job Specialty: Research Studies/Clinical Trials

Position Type: Full-time

Shift Length: 8 hour shift

Shift Type: Day

Cedars-Sinai is an EEO employer. Cedars-Sinai does not unlawfully discriminate on the basis of the race, religion, color, national origin, citizenship, ancestry, physical or mental disability, legally protected medical condition (cancer-related or genetic characteristics or any genetic information), marital status, sex, gender, sexual orientation, gender identity, gender expression, pregnancy, age (40 or older), military and/or veteran status or any other basis protected by federal or state law.

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